Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 4/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547684 | 0.81 | PIK3CD (0.37) | PIK3CDPIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL8548916 | 0.78 | ALDH1A1 (0.44) | MEN1KMT2ATDP1ALDH1A1NPSR1 | |
| SCHEMBL29941923 | 0.73 | RAB9A (0.42) | MEN1KMT2ATDP1ALDH1A1NPSR1 | |
| SCHEMBL2847202 | 0.72 | ALDH1A1 (0.51) | PIK3CDPIK3CGPIK3CAPIK3CBMEN1 | |
| SCHEMBL8548155 | 0.72 | ALDH1A1 (0.33) | MEN1KMT2ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL548482 | 0.71 | LMNA (0.48) | MEN1KMT2ATDP1ALDH1A1NPSR1 | |
| SCHEMBL4462854 | 0.71 | KMT2A (0.46) | MEN1KMT2ATDP1ALDH1A1NPSR1 | |
| SCHEMBL2822055 | 0.71 | ERN1 (0.47) | ALDH1A1NPSR1LMNAPTGS2NPC1 | |
| SCHEMBL2825578 | 0.71 | ESR1 (0.49) | TDP1ALDH1A1NPSR1LMNANPC1 | |
| SCHEMBL8550487 | 0.70 | MEN1 (0.39) | PIK3CAMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0702003-B1 | Process for preparing 2-halogenpyridinaldehydes | BAYER AG (DE) | 1998-06-17 | — | — | EP | disclosed |
| US-5708180-A | CYCLIZATION OF UNSATURATED NITRILE, AMIDE OR OXIME | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0702003-A2 | Process for preparing 2-halogenpyridinaldehydes and new 2-halogenpyridinaldehydes | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |