Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 9/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548878 | 1.00 | NPSR1 (0.43) | NPSR1SLC6A3KMT2AGAAALDH1A1 | |
| SCHEMBL8548300 | 0.89 | NPC1 (0.48) | NPSR1KMT2AALDH1A1MAPTCTSK | |
| SCHEMBL8548308 | 0.89 | NPC1 (0.48) | NPSR1KMT2AALDH1A1MAPTCTSK | |
| SCHEMBL8548109 | 0.88 | NPSR1 (0.43) | NPSR1KMT2AGAAALDH1A1CTSK | |
| SCHEMBL8548100 | 0.88 | NPSR1 (0.43) | NPSR1KMT2AGAAALDH1A1CTSK | |
| SCHEMBL8548880 | 0.86 | ALDH1A1 (0.54) | NPSR1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL8548486 | 0.84 | CTSK (0.46) | NPSR1KMT2AALDH1A1MAPTCTSK | |
| SCHEMBL8548482 | 0.84 | CTSK (0.46) | NPSR1KMT2AALDH1A1MAPTCTSK | |
| SCHEMBL8543316 | 0.83 | CTSK (0.53) | NPSR1KMT2AGAAALDH1A1MAPT | |
| SCHEMBL8543314 | 0.83 | CTSK (0.53) | NPSR1KMT2AGAAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |