SCHEMBL8548923

SCHEMBL8548923

C=CC(=O)OC(C)c1cccc(C(=O)O)c1O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
HPGD P15428 5/20 0.44
KDM4E B2RXH2 4/20 0.44
HSD17B10 Q99714 3/20 0.44
ALB P02768 1/20 0.40
MMP2 P08253 1/20 0.40
HNF4A P41235 1/20 0.38
HCAR2 Q8TDS4 1/20 0.38
KMT2A Q03164 2/20 0.36
CYP3A4 P08684 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
HMGB1 P09429 2/20 0.36
GAA P10253 1/20 0.36
CYP2C9 P11712 1/20 0.36
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
FAAH O00519 1/20 0.34
LMNA P02545 1/20 0.34
CYP1A2 P05177 1/20 0.34
GABRA1 P14867 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1564579 0.88 HCAR2 (0.38) ALDH1A1HPGDKDM4EHSD17B10HCAR2
SCHEMBL8549851 0.88 HCAR2 (0.43) ALDH1A1HPGDKDM4EHSD17B10HCAR2
SCHEMBL28875675 0.86 BCL2 (0.45) ALDH1A1HPGDKDM4EHSD17B10HCAR2
SCHEMBL7199606 0.83 FABP4 (0.40) ALDH1A1HPGDKDM4EHSD17B10HNF4A
SCHEMBL6278590 0.83 HCAR2 (0.39) ALDH1A1HPGDKDM4EHSD17B10HCAR2
SCHEMBL6536389 0.80 ALDH1A1 (0.45) ALDH1A1HPGDKDM4EHSD17B10ALB
SCHEMBL587824 0.79 SLC37A4 (0.34) ALDH1A1HPGDKDM4EHSD17B10HCAR2
SCHEMBL1906054 0.78 GABRA1 (0.46) HCAR2KMT2AGAACA1CA2
SCHEMBL26653846 0.78 BCL2 (0.41) ALDH1A1HPGDKDM4EHSD17B10HCAR2
Phthalic Acid SCHEMBL335919 0.76 ALDH1A1 (0.48) ALDH1A1HPGDKDM4EHSD17B10HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724503-B1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING & MFG (US) 1998-11-11 EP disclosed
US-5736747-A SOLUBLE CURING AGENTS FOR PHENOLIC RESINS OR PHOTOPOLYMERIZABLE MONOMER MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-04-07 US disclosed
US-5733648-A FOR AMINOPLASTS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-03-31 US disclosed
US-5710281-A Organic compounds suitable as reactive diluents and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5709935-A ACRYLATE FUNCTIONAL DILUENTS WHICH SOLUBILIZE AMINO RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1998-01-20 US disclosed
US-5667842-A Abrasive articles incorporating addition polymerizable resins and reactive diluents, and methods of making said abrasive articles MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
US-5580647-A OPEN NON-WOVEN MAT HAVING FIBERS JOINED AT POINTS OF CONTACT BY BINDER FROM ADDITION POLYMERIZABLE BINDER PRECURSOR MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-03 US disclosed
EP-0724503-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-08-07 EP disclosed
US-5523152-A Organic compounds suitable as reactive diluents, and binder precursor compositions including same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-06-04 US disclosed
WO-1995011774-A1 ABRASIVE ARTICLES INCORPORATING ADDITION POLYMERIZABLE RESINS AND REACTIVE DILUENTS, AND METHODS OF MAKING SAID ABRASIVE ARTICLES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-04 WO disclosed