Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | PPOX | P50336 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548321 | 0.90 | PPOX (0.38) | POLBL3MBTL1PPOXCYP1A2CYP2C19 | |
| SCHEMBL4681755 | 0.84 | PPOX (0.41) | POLBL3MBTL1PPOXALDH1A1CYP1A2 | |
| SCHEMBL4678732 | 0.78 | MAPK1 (0.40) | L3MBTL1PPOXALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL4681745 | 0.78 | MEN1 (0.37) | POLBL3MBTL1ALDH1A1LMNAMEN1 | |
| SCHEMBL4677762 | 0.77 | MEN1 (0.41) | POLBL3MBTL1PPOXALDH1A1CYP1A2 | |
| SCHEMBL4679256 | 0.77 | MAPK1 (0.33) | L3MBTL1PPOXALDH1A1MEN1KMT2A | |
| SCHEMBL4681716 | 0.77 | PPOX (0.55) | POLBL3MBTL1PPOXALDH1A1CYP1A2 | |
| SCHEMBL4682095 | 0.77 | PKM (0.34) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL7113369 | 0.77 | ALDH1A1 (0.44) | POLBL3MBTL1PPOXALDH1A1LMNA | |
| SCHEMBL7113367 | 0.77 | ALDH1A1 (0.44) | POLBL3MBTL1PPOXALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |