Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPOX | P50336 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548951 | 0.90 | POLB (0.43) | PPOXKMT2AMEN1L3MBTL1TP53 | |
| SCHEMBL4678732 | 0.82 | MAPK1 (0.40) | PPOXKMT2AMEN1L3MBTL1PKM | |
| SCHEMBL4682095 | 0.79 | PKM (0.34) | KMT2AMEN1L3MBTL1PKMLMNA | |
| SCHEMBL4681755 | 0.78 | PPOX (0.41) | PPOXKMT2AMEN1L3MBTL1POLB | |
| SCHEMBL4679256 | 0.77 | MAPK1 (0.33) | PPOXKMT2AMEN1L3MBTL1PKM | |
| SCHEMBL6794821 | 0.77 | PPOX (0.44) | PPOXKMT2AL3MBTL1PKMNPSR1 | |
| SCHEMBL4678988 | 0.76 | NPBWR1 (0.33) | KMT2AMEN1L3MBTL1HPGDPKM | |
| SCHEMBL5388413 | 0.75 | GAA (0.37) | KMT2AL3MBTL1HPGD | |
| SCHEMBL4681493 | 0.74 | PPOX (0.43) | PPOXKMT2AMAPK1 | |
| SCHEMBL9037487 | 0.74 | BCAT1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |