Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8545031 | 0.88 | ALDH1A1 (0.61) | FKBP1AALDH1A1SMN1; SMN2F2CYP3A4 | |
| SCHEMBL21264926 | 0.88 | MMEL1 (0.49) | FKBP1AALDH1A1SMN1; SMN2F2CYP3A4 | |
| SCHEMBL21264915 | 0.88 | MMEL1 (0.49) | FKBP1AALDH1A1SMN1; SMN2F2CYP3A4 | |
| SCHEMBL8544795 | 0.85 | FKBP1A (0.59) | FKBP1AALDH1A1SMN1; SMN2F2CYP3A4 | |
| SCHEMBL14836855 | 0.85 | MMEL1 (0.52) | FKBP1AALDH1A1SMN1; SMN2CYP2C19MMEL1 | |
| SCHEMBL22652992 | 0.85 | F2 (0.47) | FKBP1AALDH1A1SMN1; SMN2F2PTGER4 | |
| SCHEMBL21264916 | 0.85 | KMT2A (0.50) | FKBP1AALDH1A1SMN1; SMN2F2MMEL1 | |
| SCHEMBL21264924 | 0.85 | KMT2A (0.50) | FKBP1AALDH1A1SMN1; SMN2F2MMEL1 | |
| SCHEMBL8549125 | 0.84 | NPSR1 (0.48) | FKBP1AALDH1A1SMN1; SMN2HDAC1HDAC2 | |
| SCHEMBL8549128 | 0.84 | NPSR1 (0.48) | FKBP1AALDH1A1SMN1; SMN2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| JP-6041064-A | — | — | None | — | — | JP | disclosed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| JP-H0641064-A | 2-OXOETHYL DERIVATIVE | MILES INC | 1994-02-15 | — | — | JP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |