Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.48 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549125 | 1.00 | NPSR1 (0.48) | NPSR1MMEL1CTRB1MMP2MMP9 | |
| SCHEMBL8545024 | 0.86 | ALDH1A1 (0.45) | NPSR1ACEALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8545028 | 0.86 | ALDH1A1 (0.45) | NPSR1ACEALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8549131 | 0.84 | FKBP1A (0.55) | MMEL1HDAC1HDAC2HDAC3FKBP1A | |
| SCHEMBL8544794 | 0.83 | NPSR1 (0.47) | NPSR1ACEALDH1A1MAPT | |
| SCHEMBL14836855 | 0.83 | MMEL1 (0.52) | MMEL1CTRB1ACEFKBP1AALDH1A1 | |
| SCHEMBL8544789 | 0.83 | NPSR1 (0.47) | NPSR1ACEALDH1A1MAPT | |
| SCHEMBL8543316 | 0.82 | CTSK (0.53) | NPSR1ALDH1A1KMT2AMAPT | |
| SCHEMBL8543314 | 0.82 | CTSK (0.53) | NPSR1ALDH1A1KMT2AMAPT | |
| SCHEMBL8546776 | 0.82 | CTSK (0.42) | NPSR1MMEL1ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | claimed |
| JP-6041064-A | — | — | None | — | — | JP | disclosed |
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5686424-A | FOR TREATING INFLAMMATION | MILES INC. (US) | 1997-11-11 | — | — | US | disclosed |
| JP-H0641064-A | 2-OXOETHYL DERIVATIVE | MILES INC | 1994-02-15 | — | — | JP | disclosed |
| EP-0564924-A2 | 2-Oxoethyl derivatives as immunosuppressants | Bayer Corporation (US) | 1993-10-13 | — | — | EP | disclosed |