Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 9/20 | 0.44 |
| ▸ | IDH1 | O75874 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7334957 | 0.86 | LMNA (0.50) | POLBMEN1KMT2AALDH1A1 | |
| SCHEMBL7327895 | 0.86 | POLB (0.55) | ACLYIDH1POLBGAATSHR | |
| SCHEMBL7361453 | 0.74 | MAPK1 (0.52) | IDH1POLBGAATSHRMEN1 | |
| SCHEMBL8542455 | 0.73 | POLB (0.65) | IDH1POLBGAATSHRALDH1A1 | |
| SCHEMBL8542581 | 0.71 | POLB (0.59) | POLBGAATSHRMEN1KMT2A | |
| SCHEMBL7330175 | 0.68 | F2 (0.67) | POLBGAA | |
| SCHEMBL7336279 | 0.68 | F2 (0.54) | — | |
| SCHEMBL7330777 | 0.68 | PGR (0.58) | TSHRALDH1A1FABP4 | |
| SCHEMBL5274567 | 0.67 | ALOX15 (0.54) | TSHRKMT2AALDH1A1 | |
| SCHEMBL7335570 | 0.67 | CYP19A1 (0.61) | ARALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687253-B1 | 4-AMINOPYRIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS CONTAINING THE SAME | BOEHRINGER MANNHEIM GMBH (DE) | 1998-12-16 | — | — | EP | disclosed |