Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.50 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.50 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.50 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6314811 | 0.84 | GAA (0.51) | GAANPC1TP53PDK1PDK2 | |
| SCHEMBL14515393 | 0.83 | ALDH1A1 (0.52) | GAASMN1; SMN2MAPTNPC1PDK1 | |
| SCHEMBL22167747 | 0.81 | PDK1 (0.49) | KCNMA1GAASMN1; SMN2MAPTNPC1 | |
| SCHEMBL22164080 | 0.81 | PDK1 (0.49) | GAASMN1; SMN2MAPTNPC1TP53 | |
| SCHEMBL25236842 | 0.81 | PDK1 (0.49) | KCNMA1SMN1; SMN2MAPTNPC1TP53 | |
| SCHEMBL17666342 | 0.81 | MEN1 (0.61) | GAASMN1; SMN2NPC1TP53PDK1 | |
| SCHEMBL7299719 | 0.81 | MEN1 (0.49) | KCNMA1MAPTTP53HTTMEN1 | |
| SCHEMBL8550609 | 0.80 | GRIK1 (0.56) | GAASMN1; SMN2TP53PDK1PDK2 | |
| SCHEMBL6397287 | 0.80 | KCNMA1 (0.69) | KCNMA1GAASMN1; SMN2MAPTNPC1 | |
| SCHEMBL24251938 | 0.79 | MEN1 (0.47) | SMN1; SMN2MAPTNPC1HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614893-B1 | Benzoxazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1998-05-27 | — | — | EP | disclosed |
| US-5447928-A | Antiischemic agents and nervous system disorders | SYNTHELABO (FR) | 1995-09-05 | — | — | US | disclosed |
| CN-1099032-A | Benzoxazine derivatives, their preparation and their use in medicine | SYNTHELABO (FR) | 1995-02-22 | — | — | CN | disclosed |
| EP-0614893-A1 | Benzoazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |