Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8548674 | 0.86 | ALDH1A1 (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL9000076 | 0.85 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL8551230 | 0.85 | ALDH1A1 (0.44) | MAPTSMN1; SMN2ALDH1A1KDM4ELMNA | |
| SCHEMBL8557763 | 0.82 | ALDH1A1 (0.38) | MAPTSMN1; SMN2ALDH1A1KDM4ENPC1 | |
| SCHEMBL8548975 | 0.79 | ALDH1A1 (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL8546281 | 0.78 | MAPT (0.58) | MAPTSMN1; SMN2CYP3A4ALOX15CNR1 | |
| SCHEMBL679245 | 0.72 | ALDH1A1 (0.46) | MAPTSMN1; SMN2CASP1CASP7ALDH1A1 | |
| SCHEMBL27445439 | 0.72 | SMN1; SMN2 (0.43) | MAPTSMN1; SMN2CYP3A4ALDH1A1KDM4E | |
| SCHEMBL12013388 | 0.70 | HTT (0.47) | MAPTSMN1; SMN2CASP1CASP7ALDH1A1 | |
| SCHEMBL9070589 | 0.69 | CA12 (0.43) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |