Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.43 |
| ▸ | HPGD | P15428 | 9/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549320 | 0.79 | MAPT (0.46) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL8545930 | 0.69 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL679245 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL8546281 | 0.68 | MAPT (0.58) | ALDH1A1KDM4EHPGDHSD17B10TUBB4A | |
| SCHEMBL8548674 | 0.68 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL27445439 | 0.68 | SMN1; SMN2 (0.43) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL12013388 | 0.66 | HTT (0.47) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL9070589 | 0.65 | CA12 (0.43) | ALDH1A1KDM4EHPGDNPSR1SMN1; SMN2 | |
| SCHEMBL4437800 | 0.65 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10NPSR1 | |
| SCHEMBL5964314 | 0.65 | HTT (0.46) | ALDH1A1KDM4EHPGDNPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |