Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8549320 | 0.86 | MAPT (0.46) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL9000076 | 0.81 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDTHRBSMN1; SMN2 | |
| SCHEMBL8551230 | 0.81 | ALDH1A1 (0.44) | ALDH1A1KDM4EHPGDCA12CA9 | |
| SCHEMBL8545930 | 0.79 | ALDH1A1 (0.40) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL8557763 | 0.76 | ALDH1A1 (0.38) | ALDH1A1KDM4EHPGDTHRBCA12 | |
| SCHEMBL8308344 | 0.70 | ALDH1A1 (0.47) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL4437800 | 0.69 | ALDH1A1 (0.52) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL8548975 | 0.68 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDHSD17B10USP2 | |
| SCHEMBL12013388 | 0.68 | HTT (0.47) | ALDH1A1KDM4EHPGDHSD17B10CA12 | |
| SCHEMBL679245 | 0.68 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDHSD17B10THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |