SCHEMBL13857071

SCHEMBL13857071

ClCc1ccc(Oc2cccc(Cc3cccc(Oc4ccc(CCl)cc4)c3)c2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HTT P42858 2/20 0.46
TTR P02766 1/20 0.42
MEN1 O00255 1/20 0.42
MITF O75030 1/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
NLRP1 Q9C000 1/20 0.42
NOD2 Q9HC29 1/20 0.42
ST14 Q9Y5Y6 1/20 0.42
FFAR1 O14842 2/20 0.42
FFAR4 Q5NUL3 1/20 0.42
SRD5A2 P31213 1/20 0.42
LTA4H P09960 1/20 0.41
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11178465 0.89 SRD5A2 (0.51) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL8549352 0.88 ALDH1A1 (0.54) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL9502073 0.86 ALDH1A1 (0.48) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL9816693 0.85 SRD5A2 (0.58) ALDH1A1KDM4ESMN1; SMN2HTTFFAR1
SCHEMBL18422515 0.84 TTR (0.46) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL9502164 0.83 FDFT1 (0.50) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL81395 0.82 TTR (0.54) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL30132325 0.82 TTR (0.54) ALDH1A1KDM4ESMN1; SMN2HTTTTR
SCHEMBL8896665 0.82 TSHR (0.55) ALDH1A1KDM4ESMN1; SMN2HTTMEN1
SCHEMBL11318601 0.81 ALDH1A1 (0.56) ALDH1A1KDM4ESMN1; SMN2HTTTTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-8436103-B2 Star polymer and method of producing the same NIPPON SODA CO., LTD. (JP) 2013-05-07 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed
US-20090118436-A1 Star Polymer and Method of Producing the Same NIPPON SODA CO., LTD. (JP) 2009-05-07 US disclosed