Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 7/20 | 0.41 |
| ▸ | DCUN1D1 | Q96GG9 | 7/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484990 | 0.83 | CCR2 (0.43) | UBE2MDCUN1D1CCR3 | |
| SCHEMBL8548733 | 0.83 | DCUN1D1 (0.41) | UBE2MDCUN1D1CCR3 | |
| SCHEMBL8703019 | 0.74 | DRD2 (0.53) | UBE2MDCUN1D1CCR3RAB9ABCHE | |
| SCHEMBL8703742 | 0.73 | DCUN1D1 (0.45) | UBE2MDCUN1D1CCR3RAB9A | |
| SCHEMBL8702974 | 0.71 | DRD2 (0.53) | UBE2MDCUN1D1CCR3RAB9ABCHE | |
| SCHEMBL8547062 | 0.69 | DRD2 (0.46) | UBE2MDCUN1D1CCR3 | |
| SCHEMBL8707882 | 0.69 | DRD2 (0.54) | — | |
| SCHEMBL8552992 | 0.68 | RAB9A (0.44) | RAB9ABCHE | |
| SCHEMBL8703834 | 0.68 | DRD2 (0.46) | UBE2MDCUN1D1BCHE | |
| SCHEMBL7474419 | 0.67 | HTR1D (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |