Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.44 |
| ▸ | NPC1 | O15118 | 9/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551266 | 0.81 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7487964 | 0.80 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8553059 | 0.70 | DRD2 (0.42) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8553525 | 0.68 | DRD2 (0.43) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8549604 | 0.68 | UBE2M (0.41) | RAB9ABCHE | |
| SCHEMBL8548376 | 0.68 | DRD2 (0.42) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10156184 | 0.68 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL10157334 | 0.68 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL8381703 | 0.66 | RAB9A (0.41) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL17340327 | 0.66 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5792763-A | MIGRAINES; ANALGESICS; DISEASES LINKED TO DECREASED NEUROTRANMISSION OF SEROTONIN IN MAMMALS | ELI LILLY AND COMPANY (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |