Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | ACE | P12821 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499066 | 0.87 | ELANE (0.64) | ELANECTRB1APPITGB3ITGA2B | |
| SCHEMBL8543203 | 0.82 | CTRB1 (0.57) | ELANECTRB1P2RX7LCKEPHX2 | |
| SCHEMBL8549802 | 0.80 | MAPT (0.51) | ELANECTRB1ACEALDH1A1CTSS | |
| SCHEMBL7830822 | 0.80 | ELANE (0.61) | ELANECTRB1LCKALDH1A1 | |
| SCHEMBL6496223 | 0.79 | ELANE (0.72) | ELANECTRB1APPACEPTPN1 | |
| SCHEMBL6498011 | 0.78 | ELANE (0.63) | ELANECTRB1APPITGB3ITGA2B | |
| SCHEMBL6498666 | 0.78 | ELANE (0.62) | ELANECTRB1APPACELCK | |
| SCHEMBL7659173 | 0.77 | ATM (0.43) | ELANEPPARGMEN1ALDH1A1KMT2A | |
| SCHEMBL8545041 | 0.77 | ELANE (0.43) | ELANECTRB1PPARGPPARAMEN1 | |
| SCHEMBL6503996 | 0.77 | ELANE (0.60) | ELANECTRB1APPITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |