Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6507056 | 0.86 | CTRB1 (0.51) | ATMKMT2AMEN1RAB9AMAPT | |
| SCHEMBL8549217 | 0.84 | ELANE (0.41) | ATMKMT2AMEN1MAPTHPGD | |
| SCHEMBL8545041 | 0.84 | ELANE (0.43) | KMT2AMEN1ELANEALDH1A1PPARG | |
| SCHEMBL8550797 | 0.81 | ALDH1A1 (0.42) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL8545895 | 0.77 | ALDH1A1 (0.50) | KMT2AMEN1ELANETSHRALDH1A1 | |
| SCHEMBL8549764 | 0.77 | ELANE (0.47) | KMT2AMEN1ELANEALDH1A1PPARG | |
| SCHEMBL6497371 | 0.72 | NPC1 (0.47) | KMT2AMEN1RAB9AMAPTNPC1 | |
| SCHEMBL6496066 | 0.72 | CTRB1 (0.67) | ATMKMT2AMEN1RAB9AMAPT | |
| SCHEMBL7813812 | 0.71 | CTRB1 (0.52) | KMT2AMEN1RAB9ANPC1HPGD | |
| SCHEMBL6499604 | 0.71 | CTRB1 (0.56) | KMT2AMEN1SMN1; SMN2ELANEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380189-B1 | FOR TREATING HERPES-RELATED DISORDERS | G.D. SEARLE & CO. | 2002-04-30 | — | — | US | disclosed |
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |