Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8543951 | 0.99 | L3MBTL1 (0.45) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL8546963 | 0.84 | OPRM1 (0.50) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| Hydrochloric Acid SCHEMBL8549158 | 0.83 | OPRM1 (0.49) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL8545368 | 0.78 | L3MBTL1 (0.51) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| Hydrochloric Acid SCHEMBL8550390 | 0.77 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL7823257 | 0.76 | ALDH1A1 (0.61) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL6461487 | 0.73 | SMN1; SMN2 (0.48) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL709246 | 0.71 | TDP1 (0.60) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL969334 | 0.70 | TDP1 (0.59) | L3MBTL1SMN1; SMN2LMNAHTTTDP1 | |
| SCHEMBL7815654 | 0.70 | ALDH1A1 (0.54) | L3MBTL1LMNAALDH1A1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0564924-B1 | 2-Oxoethyl derivatives as immunosuppressants | BAYER AG (US) | 1998-09-09 | — | — | EP | claimed |