Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4437800 | 0.87 | ALDH1A1 (0.52) | SLC22A12ALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL12013388 | 0.86 | HTT (0.47) | SLC22A12ALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL679245 | 0.86 | ALDH1A1 (0.46) | SLC22A12ALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL8551230 | 0.81 | ALDH1A1 (0.44) | SLC22A12ALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL5964314 | 0.80 | HTT (0.46) | SLC22A12ALDH1A1NPSR1L3MBTL1HTT | |
| SCHEMBL8543822 | 0.78 | CASP1 (0.52) | SLC22A12ALDH1A1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL8550034 | 0.76 | KDM4E (0.46) | SLC22A12ALDH1A1PKMMAPTSMN1; SMN2 | |
| SCHEMBL8544863 | 0.76 | KDM4E (0.58) | SLC22A12ALDH1A1PKMMAPTSMN1; SMN2 | |
| SCHEMBL8308344 | 0.75 | ALDH1A1 (0.47) | ALDH1A1NPSR1L3MBTL1HTTPKM | |
| SCHEMBL8550539 | 0.74 | SLC22A12 (0.41) | SLC22A12ALDH1A1NPSR1L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623607-B1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1998-07-15 | — | — | EP | disclosed |
| US-5504213-A | ANTIINFLAMMATORY AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| EP-0623607-A1 | Benzofuranyl-and-thiophenyl-alkanecarboxyclic acid derivatives | BAYER AG (DE) | 1994-11-09 | — | — | EP | disclosed |