Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914392 | 0.82 | HDAC4 (0.31) | — | |
| SCHEMBL314331 | 0.80 | LMNA (0.38) | L3MBTL1MEN1KMT2A | |
| SCHEMBL17914413 | 0.75 | HTT (0.30) | — | |
| SCHEMBL10784340 | 0.72 | LMNA (0.40) | L3MBTL1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL2376977 | 0.71 | CES2 (0.53) | L3MBTL1ALDH1A1CTNNB1WNT3AHPGD | |
| SCHEMBL28722327 | 0.71 | DDB1 (0.55) | ALDH1A1CYP19A1 | |
| SCHEMBL2636367 | 0.70 | ACHE (0.50) | ALDH1A1MAPTCES2CES1 | |
| SCHEMBL2534644 | 0.69 | ACHE (0.48) | ALDH1A1MAPTCES2CES1 | |
| SCHEMBL8367527 | 0.69 | ACHE (0.48) | ALDH1A1MAPTCES2CES1 | |
| SCHEMBL6897457 | 0.69 | ACHE (0.48) | ALDH1A1MAPTCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842161-A1 | 4,5-DIARYL OXAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-20 | — | — | EP | disclosed |