Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7231866 | 1.00 | CYP19A1 (0.35) | CYP19A1NR1D1ELANEALDH1A1HPGD | |
| SCHEMBL7231891 | 0.87 | CYP19A1 (0.34) | CYP19A1ALDH1A1 | |
| SCHEMBL7235416 | 0.83 | CYP19A1 (0.38) | CYP19A1NR1D1ELANEALDH1A1HPGD | |
| SCHEMBL7234258 | 0.81 | CYP19A1 (0.35) | CYP19A1NR1D1 | |
| SCHEMBL7234703 | 0.80 | MTNR1A (0.37) | CYP19A1 | |
| SCHEMBL8547281 | 0.79 | KEAP1 (0.32) | CYP19A1 | |
| SCHEMBL7234235 | 0.77 | CYP3A4 (0.35) | CYP19A1ALDH1A1 | |
| SCHEMBL7239236 | 0.76 | NR1H2 (0.35) | CYP19A1SIGMAR1 | |
| SCHEMBL9132239 | 0.76 | NR1H2 (0.35) | CYP19A1SIGMAR1 | |
| SCHEMBL9132827 | 0.76 | NPSR1 (0.43) | CYP19A1ELANEALDH1A1HPGDSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842151-A1 | 4-MERCAPTOPYRROLIDINE DERIVATIVES AS FARNESYL TRANSFERASE INHIBITORS | ZENECA LIMITED (GB) | 1998-05-20 | — | — | EP | disclosed |