Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553301 | 0.88 | PDE2A (0.36) | — | |
| SCHEMBL8552697 | 0.88 | TDP1 (0.38) | LMNATP53MAPT | |
| SCHEMBL8552377 | 0.88 | SMN1; SMN2 (0.37) | LMNATP53MAPT | |
| SCHEMBL8552341 | 0.86 | PDE2A (0.33) | — | |
| SCHEMBL8551648 | 0.83 | LMNA (0.31) | LMNATP53MAPT | |
| SCHEMBL8552056 | 0.83 | LMNA (0.31) | LMNATP53MAPT | |
| SCHEMBL8551855 | 0.80 | NLRP3 (0.32) | MAPT | |
| SCHEMBL8551378 | 0.77 | KDM4E (0.35) | LMNATP53MAPT | |
| SCHEMBL8550783 | 0.76 | USP2 (0.34) | — | |
| SCHEMBL8548822 | 0.74 | TDP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |