Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552697 | 0.89 | TDP1 (0.38) | NPSR1 | |
| SCHEMBL8550150 | 0.88 | LMNA (0.34) | — | |
| SCHEMBL8552377 | 0.87 | SMN1; SMN2 (0.37) | PDE2AKMT2AMEN1 | |
| SCHEMBL8552341 | 0.87 | PDE2A (0.33) | PDE2A | |
| SCHEMBL8549196 | 0.84 | PDE2A (0.35) | PDE2A | |
| SCHEMBL8550106 | 0.83 | PDE2A (0.35) | PDE2A | |
| SCHEMBL8553303 | 0.82 | S1PR4 (0.33) | PDE2AKMT2A | |
| SCHEMBL8551855 | 0.81 | NLRP3 (0.32) | — | |
| SCHEMBL8550783 | 0.78 | USP2 (0.34) | — | |
| SCHEMBL8551378 | 0.77 | KDM4E (0.35) | NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5708013-A | BENZIMIDAZOLESULFOXIDE DERIVATIVES | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |