Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GPR183 | P32249 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550448 | 1.00 | CPB1 (0.37) | CPB1KDM2BNPC1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8595164 | 0.87 | TDP1 (0.35) | CPB1KDM2BNPC1GPR183ALDH1A1 | |
| SCHEMBL8551437 | 0.76 | CPB1 (0.37) | CPB1KDM2BPOLB | |
| SCHEMBL19589409 | 0.70 | CPB1 (0.39) | CPB1KDM2BMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL8553117 | 0.69 | NPC1 (0.36) | CPB1KDM2BNPC1ALDH1A1CYP1A2 | |
| SCHEMBL8554405 | 0.69 | CDK5 (0.47) | CPB1KDM2B | |
| SCHEMBL3282448 | 0.66 | SIGMAR1 (0.44) | MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13406413 | 0.65 | KDM2B (0.49) | CPB1KDM2B | |
| Hydrochloric Acid SCHEMBL8552568 | 0.65 | MAP3K7 (0.35) | CPB1NPC1ALDH1A1 | |
| SCHEMBL15329249 | 0.63 | CPB2 (0.36) | KDM2BNPC1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |