Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 9/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 9/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DEGS1 | O15121 | 3/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | CPB1 | P15086 | 1/20 | 0.37 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8592153 | 0.88 | CDK5 (0.46) | CDK5CDK5R1GSK3BDEGS1USP30 | |
| SCHEMBL8554188 | 0.76 | CDK5 (0.43) | CDK5CDK5R1GSK3BCPB1KDM2B | |
| SCHEMBL8551437 | 0.69 | CPB1 (0.37) | CPB1KDM2B | |
| SCHEMBL8550443 | 0.69 | CPB1 (0.37) | CPB1KDM2B | |
| SCHEMBL8550448 | 0.69 | CPB1 (0.37) | CPB1KDM2B | |
| Hydrochloric Acid SCHEMBL8618549 | 0.69 | SMN1; SMN2 (0.45) | CDK5CDK5R1GSK3B | |
| SCHEMBL1269214 | 0.67 | CDK5 (0.57) | CDK5CDK5R1GSK3BKDM2B | |
| Hydrochloric Acid SCHEMBL8551563 | 0.67 | CDK5 (0.38) | CDK5CDK5R1GSK3BCPB1KDM2B | |
| SCHEMBL13406413 | 0.65 | KDM2B (0.49) | CDK5CDK5R1CPB1KDM2B | |
| SCHEMBL3282448 | 0.63 | SIGMAR1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0858457-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | Dr. Karl Thomae GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997015567-A1 | 5-MEMBERED HETEROCYCLES, PHARMACEUTICAL AGENTS CONTAINING SAID COMPOUNDS AND THE USE THEREOF AND METHODS OF PRODUCING THEM | DR. KARL THOMAE GMBH (DE) | 1997-05-01 | — | — | WO | disclosed |