Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 13/20 | 0.43 |
| ▸ | RXRA | P19793 | 10/20 | 0.43 |
| ▸ | RXRB | P28702 | 8/20 | 0.43 |
| ▸ | RXRG | P48443 | 4/20 | 0.37 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.36 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9097865 | 0.86 | NR4A2 (0.41) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8556768 | 0.79 | NR4A2 (0.45) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL9097717 | 0.78 | RXRA (0.41) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL9098566 | 0.77 | RXRA (0.54) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8552554 | 0.77 | RXRA (0.39) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8552261 | 0.77 | NR4A2 (0.45) | NR4A2RXRARXRBNR4A1NR4A3 | |
| SCHEMBL8560532 | 0.76 | RXRA (0.46) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8551313 | 0.76 | NR4A2 (0.41) | NR4A2RXRARXRBRXRGNR4A1 | |
| SCHEMBL8555499 | 0.76 | RXRA (0.49) | NR4A2RXRARXRBRXRG | |
| SCHEMBL8561401 | 0.76 | MAOB (0.41) | NR4A2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |