SCHEMBL8550625

SCHEMBL8550625

CCc1nnsc1OC(=O)Cl

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ABCC8 Q09428 5/20 0.34
KCNJ11 Q14654 5/20 0.34
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9527148 0.69 KDM4E (0.33) TSHR
SCHEMBL11205222 0.69 LMNA (0.33) TSHR
SCHEMBL4950895 0.66 ABCC8 (0.47) ABCC8KCNJ11
SCHEMBL10918558 0.64 MAPT (0.35) TSHR
SCHEMBL12321791 0.63
Tert-Butylamine SCHEMBL4952237 0.61 ABCC8 (0.43) ABCC8KCNJ11
SCHEMBL13480534 0.61
SCHEMBL8597243 0.59 LMNA (0.48) TSHR
SCHEMBL4950787 0.59 TSHR (0.44) TSHR
SCHEMBL2901849 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0865441-A1 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS AND THE USE THEREOF AS A PEST CONTROL AGENT OR AS A MICROBICIDE BAYER AG (DE) 1998-09-23 EP disclosed
WO-1997020840-A1 1,2,3-THIADIAZOLE CARBOXYLIC ACID (THIO)ESTERS AND THE USE THEREOF AS A PEST CONTROL AGENT OR AS A MICROBICIDE BAYER AKTIENGESELLSCHAFT (DE) 1997-06-12 WO disclosed