Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526569 | 0.88 | LMNA (0.36) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9446207 | 0.80 | KDM4E (0.36) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9446210 | 0.76 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9446238 | 0.73 | LMNA (0.40) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL8550625 | 0.69 | ABCC8 (0.34) | TSHR | |
| SCHEMBL9446209 | 0.69 | LMNA (0.44) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL9526057 | 0.67 | ACACB (0.31) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11133645 | 0.62 | PDE4D (0.51) | KDM4ELMNAL3MBTL1MAPTKMT2A | |
| SCHEMBL27193009 | 0.61 | NPSR1 (0.36) | ALDH1A1HPGDLMNAHTTL3MBTL1 | |
| SCHEMBL2901849 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337263-B1 | ISOXAZOL(ISOTHIAZOLS)-5-CARBOXAMIDES | BASF Aktiengesellschaft (DE) | 1993-03-17 | — | — | EP | disclosed |
| EP-0337263-A2 | Isoxazol(isothiazols)-5-carboxamides | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |