Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL557654 | 0.66 | KDM1A (0.53) | — | |
| SCHEMBL8550674 | 0.60 | DRD4 (0.40) | — | |
| SCHEMBL28265607 | 0.54 | ERN1 (0.58) | — | |
| SCHEMBL6860500 | 0.53 | ALDH1A1 (0.52) | — | |
| SCHEMBL420380 | 0.53 | CDK4 (0.54) | CDK4CCND1 | |
| SCHEMBL14234959 | 0.52 | KDM4E (0.33) | — | |
| SCHEMBL28274202 | 0.52 | MAOA (0.42) | — | |
| SCHEMBL27962998 | 0.52 | ALDH1A1 (0.50) | — | |
| SCHEMBL23630584 | 0.51 | KDM1A (0.78) | — | |
| SCHEMBL25180036 | 0.51 | MAPT (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0560231-B1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST MARION ROUSSEL INC (US) | 1998-06-03 | — | — | EP | disclosed |
| EP-0560231-A1 | Pyrazolo(3,4-a)acridine derivatives as analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-09-15 | — | — | EP | disclosed |
| US-5179100-A | Analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-01-12 | — | — | US | disclosed |