Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9190729 | 0.96 | NPC1 (0.49) | NPC1LMNASMN1; SMN2ALDH1A1GRIN1 | |
| SCHEMBL9190735 | 0.83 | ABCB1 (0.46) | ALDH1A1GRIN1GRIN2BNPSR1MAPT | |
| SCHEMBL8541700 | 0.76 | LMNA (0.64) | NPC1LMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8548625 | 0.75 | LMNA (0.63) | NPC1LMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL8542630 | 0.73 | LMNA (0.62) | LMNAALDH1A1GRIN1GRIN2BNPSR1 | |
| SCHEMBL8546477 | 0.71 | LMNA (0.51) | LMNAALDH1A1NPSR1MAPTMEN1 | |
| SCHEMBL8543224 | 0.70 | LMNA (0.65) | NPC1LMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL12719840 | 0.70 | PKM (0.56) | LMNAALDH1A1PKMNPSR1MEN1 | |
| Hydrochloric Acid SCHEMBL1628132 | 0.69 | PKM (0.55) | LMNAALDH1A1PKMNPSR1MEN1 | |
| SCHEMBL8543754 | 0.68 | LMNA (0.64) | LMNASMN1; SMN2ALDH1A1NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0614893-B1 | Benzoxazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1998-05-27 | — | — | EP | disclosed |
| US-5447928-A | Antiischemic agents and nervous system disorders | SYNTHELABO (FR) | 1995-09-05 | — | — | US | disclosed |
| EP-0614893-A1 | Benzoazine derivatives, their preparation and their use in therapy | SYNTHELABO (FR) | 1994-09-14 | — | — | EP | disclosed |