Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | JAK1 | P23458 | 1/20 | 0.45 |
| ▸ | TYK2 | P29597 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551161 | 1.00 | GFER (0.53) | GFERHSD17B10FGFR1THRBMEN1 | |
| SCHEMBL6585289 | 0.81 | ALDH1A1 (0.59) | GFERFGFR1MEN1POLBKMT2A | |
| SCHEMBL6585280 | 0.81 | ALDH1A1 (0.59) | GFERFGFR1MEN1POLBKMT2A | |
| SCHEMBL8550750 | 0.80 | KDM4E (0.64) | GFERMEN1POLBKMT2AGAA | |
| SCHEMBL6583378 | 0.80 | KDM4E (0.64) | GFERMEN1POLBKMT2AGAA | |
| SCHEMBL6583386 | 0.80 | KDM4E (0.64) | GFERMEN1POLBKMT2AGAA | |
| Hydrochloric Acid SCHEMBL6581363 | 0.80 | ALDH1A1 (0.58) | GFERFGFR1MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL6581370 | 0.80 | ALDH1A1 (0.58) | GFERFGFR1MEN1POLBKMT2A | |
| SCHEMBL5809308 | 0.79 | FGFR1 (0.57) | HSD17B10FGFR1THRBMEN1KMT2A | |
| SCHEMBL8551282 | 0.78 | PDE10A (0.54) | GFERFGFR1MEN1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846689-A1 | Benzimidazole compounds | PFIZER INC. (US) | 1998-06-10 | — | — | EP | disclosed |