Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 6/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.34 |
| ▸ | GAA | P10253 | 9/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | RAD52 | P43351 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145107 | 0.86 | MAPT (0.43) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL8547927 | 0.85 | ROCK1 (0.37) | ROCK1EGFRLCKCSF1RKDR | |
| SCHEMBL8548082 | 0.85 | MKNK1 (0.38) | EGFRLCKCSF1RKDRERBB4 | |
| SCHEMBL8550959 | 0.80 | KDM4E (0.39) | ROCK1KDM4EGAAMAPTRAD52 | |
| SCHEMBL8550329 | 0.80 | KDM4E (0.40) | ROCK1EGFRLCKCSF1RKDR | |
| SCHEMBL8546411 | 0.78 | ROCK2 (0.37) | ROCK1EGFRLCKCSF1RKDR | |
| SCHEMBL8550195 | 0.75 | MEN1 (0.44) | ROCK1KDM4EGAAMAPTALDH1A1 | |
| SCHEMBL8552082 | 0.72 | KDM4E (0.45) | KDM4EGAAMAPTLMNAALDH1A1 | |
| SCHEMBL8194168 | 0.70 | TLR9 (0.43) | SMN1; SMN2RAB9A | |
| SCHEMBL8704913 | 0.70 | MKNK1 (0.38) | EGFRLCKCSF1RKDRERBB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |