Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547854 | 0.86 | SMN1; SMN2 (0.45) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL7141711 | 0.86 | SMN1; SMN2 (0.45) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL8550370 | 0.75 | KDM4E (0.41) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL8553305 | 0.74 | SMN1; SMN2 (0.42) | KDM4EGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL8550959 | 0.73 | KDM4E (0.39) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL8551238 | 0.72 | ROCK1 (0.37) | KDM4EGAAMAPTSMN1; SMN2LMNA | |
| SCHEMBL8552755 | 0.71 | KDM4E (0.43) | KDM4EGAAMAPTLMNAHTT | |
| SCHEMBL8548549 | 0.65 | HTR1F (0.50) | MAPTSMN1; SMN2POLB | |
| SCHEMBL8551920 | 0.64 | ATM (0.46) | KDM4EMAPTSMN1; SMN2LMNAHTT | |
| SCHEMBL3015930 | 0.62 | SIGMAR1 (0.58) | SMN1; SMN2LMNAHTTALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |