Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667543 | 0.87 | HTR1F (0.44) | ALDH1A1PRMT3GSK3BABL1 | |
| SCHEMBL8546411 | 0.87 | ROCK2 (0.37) | PRMT3ROCK2EGFRLCKCSF1R | |
| SCHEMBL8191020 | 0.85 | HTR1F (0.42) | KDM4EALDH1A1GAASMN1; SMN2PRMT3 | |
| SCHEMBL8551238 | 0.80 | ROCK1 (0.37) | KDM4EALDH1A1GAASMN1; SMN2PRMT3 | |
| SCHEMBL8553305 | 0.79 | SMN1; SMN2 (0.42) | KDM4EALDH1A1GAASMN1; SMN2AAK1 | |
| SCHEMBL8550195 | 0.78 | MEN1 (0.44) | KDM4EALDH1A1GAASMN1; SMN2GLA | |
| SCHEMBL8551309 | 0.76 | RAB9A (0.48) | KDM4EALDH1A1GAASMN1; SMN2GBA1 | |
| Acetic Acid SCHEMBL8548884 | 0.76 | JAK2 (0.39) | KDM4EALDH1A1GAASMN1; SMN2GLA | |
| SCHEMBL8548082 | 0.75 | MKNK1 (0.38) | EGFRLCKCSF1RKDRERBB4 | |
| SCHEMBL8550531 | 0.75 | EGFR (0.42) | KDM4EALDH1A1GAASMN1; SMN2AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523294-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | FIDIA S.P.A. (IT) | 1996-06-04 | — | — | US | claimed |
| EP-0410881-A2 | Semisynthetic ganglioside analogues | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | claimed |
| EP-0410883-A2 | Di-lysogangliosides derivatives | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | claimed |
| EP-0410883-B1 | Di-lysogangliosides derivatives | FIDIA SPA (IT) | 1999-03-31 | — | — | EP | disclosed |
| EP-0433112-B1 | Modified gangliosides and the functional derivatives thereof | FIDIA SPA (IT) | 1998-10-28 | — | — | EP | disclosed |
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |
| EP-0410881-B1 | Semisynthetic ganglioside analogues | FIDIA SPA (IT) | 1997-09-17 | — | — | EP | disclosed |
| US-5523294-A | THERAPY FOR NERVOUS SYSTEM DISORDERS | FIDIA S.P.A. (IT) | 1996-06-04 | — | — | US | disclosed |
| US-5484775-A | FOR INHIBITING GLUTAMATE-INDUCED NEUROTOXICITY | FIDIA S.P.A. (IT) | 1996-01-16 | — | — | US | disclosed |
| US-5424294-A | Treating central and peripheral nervous system disorders | FIDIA S.P.A. (IT) | 1995-06-13 | — | — | US | disclosed |
| US-5264424-A | Modified gangliosides and the functional derivatives thereof | FIDIA S.P.A. (IT) | 1993-11-23 | — | — | US | disclosed |
| EP-0433112-A1 | Modified gangliosides and the functional derivatives thereof | FIDIA S.p.A. (IT) | 1991-06-19 | — | — | EP | disclosed |
| EP-0410881-A2 | Semisynthetic ganglioside analogues | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | disclosed |
| EP-0410883-A2 | Di-lysogangliosides derivatives | FIDIA S.p.A. (IT) | 1991-01-30 | — | — | EP | disclosed |
| EP-0373039-A2 | New lysoganglioside derivatives | FIDIA S.p.A. (IT) | 1990-06-13 | — | — | EP | disclosed |