Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550889 | 0.84 | HTR6 (0.38) | ALDH1A1ROCK1HTR6IKBKBJAK2 | |
| SCHEMBL7138773 | 0.84 | IMPDH2 (0.45) | MEN1KMT2AALDH1A1ROCK1MAPT | |
| SCHEMBL8550329 | 0.78 | KDM4E (0.40) | ALDH1A1ROCK1KDM4EGLAGAA | |
| SCHEMBL8546411 | 0.76 | ROCK2 (0.37) | MEN1KMT2AROCK1MAPTROCK2 | |
| SCHEMBL8551238 | 0.75 | ROCK1 (0.37) | ALDH1A1ROCK1MAPTKDM4EGAA | |
| SCHEMBL8549181 | 0.73 | ROCK2 (0.42) | MEN1KMT2AROCK1ROCK2 | |
| SCHEMBL8553359 | 0.73 | HIF1A (0.42) | MEN1KMT2AALDH1A1PKMUSP2 | |
| SCHEMBL6667543 | 0.68 | HTR1F (0.44) | KMT2AALDH1A1MAPTCYP1A2CYP2D6 | |
| SCHEMBL10356533 | 0.67 | LMNA (0.69) | MEN1KMT2AALDH1A1PKMROCK1 | |
| Acetic Acid SCHEMBL8552677 | 0.66 | MEN1 (0.36) | MEN1KMT2AALDH1A1PKMUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998015545-A1 | NEW SEROTONIN 5-HT1F AGONISTS | ELI LILLY AND COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |