Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7478405 | 0.78 | ALDH1A1 (0.51) | HTTSLC6A2SLC6A3ALDH1A1L3MBTL1 | |
| SCHEMBL1934716 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1 | |
| SCHEMBL339812 | 0.74 | MAPT (0.71) | HTR1ASLC6A2SLC6A3LIPEL3MBTL1 | |
| SCHEMBL8473466 | 0.73 | ALOX12 (0.41) | ALDH1A1MAPK1SMN1; SMN2MEN1KMT2A | |
| Formaldehyde SCHEMBL27831678 | 0.72 | MAPT (0.63) | HTR1ALIPEL3MBTL1MAPTMAPK1 | |
| SCHEMBL7478408 | 0.70 | KMT2A (0.55) | SLC6A2SLC6A3ALDH1A1L3MBTL1MAPT | |
| SCHEMBL23258867 | 0.69 | MAPT (0.59) | HTR1ALIPEL3MBTL1MAPTMAPK1 | |
| SCHEMBL27286576 | 0.69 | MAPT (0.59) | HTR1ASLC6A2SLC6A3LIPEL3MBTL1 | |
| SCHEMBL12379257 | 0.69 | HTR1A (0.51) | HTTHTR1AALDH1A1L3MBTL1MAPT | |
| SCHEMBL5538708 | 0.68 | MAPT (0.63) | HTR1ASLC6A2SLC6A3LIPEL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840725-A1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF ATHEROSCLEROSIS | SMITHKLINE BEECHAM PLC (GB) | 1998-05-13 | — | — | EP | disclosed |