Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 2/20 | 0.51 |
| ▸ | RXRB | P28702 | 2/20 | 0.51 |
| ▸ | RXRG | P48443 | 2/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550690 | 0.86 | CA1 (0.55) | MAOBRXRARXRBRXRGCA12 | |
| SCHEMBL7499991 | 0.84 | RXRA (0.55) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8546163 | 0.83 | RXRA (0.76) | RXRARXRBRXRGPTGS2PTGS1 | |
| SCHEMBL7505499 | 0.83 | PTGS2 (0.54) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL7506769 | 0.83 | PTGS2 (0.54) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8547846 | 0.82 | PTGS1 (0.77) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8547018 | 0.81 | CA1 (0.55) | MAOBRXRARXRBRXRGCA12 | |
| SCHEMBL8550703 | 0.81 | PTGS2 (0.54) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8546261 | 0.81 | RXRA (0.53) | MAOAMAOBRXRARXRBRXRG | |
| SCHEMBL8548227 | 0.81 | PTGS1 (0.72) | MAOAMAOBRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | claimed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |