Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.55 |
| ▸ | CA2 | P00918 | 4/20 | 0.55 |
| ▸ | RXRA | P19793 | 7/20 | 0.53 |
| ▸ | RXRB | P28702 | 7/20 | 0.53 |
| ▸ | RXRG | P48443 | 7/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8547018 | 0.95 | CA1 (0.55) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL8552563 | 0.88 | CA2 (0.52) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL8550703 | 0.86 | PTGS2 (0.54) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL8551262 | 0.86 | MAOA (0.53) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL7506071 | 0.86 | RXRA (0.55) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL7506769 | 0.86 | PTGS2 (0.54) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL7505499 | 0.86 | PTGS2 (0.54) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL8552080 | 0.84 | CA2 (0.52) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL7504566 | 0.81 | RXRA (0.55) | CA1CA2RXRARXRBRXRG | |
| SCHEMBL7506528 | 0.79 | RXRA (0.47) | CA1CA2RXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | claimed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | claimed |
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036617-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1996-11-21 | — | — | WO | disclosed |