Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 7/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6505705 | 0.81 | ELANE (0.49) | ELANECTRB1 | |
| SCHEMBL6505013 | 0.81 | ELANE (0.49) | ELANECTRB1 | |
| SCHEMBL8545278 | 0.80 | ELANE (0.47) | ELANEALDH1A1USP2LMNAHSD17B10 | |
| SCHEMBL8551382 | 0.80 | ELANE (0.47) | ELANEALDH1A1USP2LMNAHSD17B10 | |
| SCHEMBL8543203 | 0.77 | CTRB1 (0.57) | ELANECTRB1CA12CA1CA9 | |
| SCHEMBL8546542 | 0.74 | ELANE (0.42) | ELANEALDH1A1LMNAHSD17B10CTRB1 | |
| SCHEMBL11100838 | 0.71 | RAB9A (0.51) | ALDH1A1HSD17B10 | |
| SCHEMBL8548636 | 0.71 | MMP12 (0.41) | ALDH1A1CTRB1CA12CA1CA2 | |
| SCHEMBL16972931 | 0.69 | NPC1 (0.54) | ELANEALDH1A1USP2LMNAHSD17B10 | |
| SCHEMBL11099522 | 0.69 | NPC1 (0.54) | ELANEALDH1A1USP2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828721-A1 | 2-AMINO-BENZOXAZINONES FOR THE TREATMENT OF VIRAL INFECTIONS | G.D. SEARLE & CO. (US) | 1998-03-18 | — | — | EP | disclosed |