Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | STAT1 | P42224 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272773 | 0.85 | RAB9A (0.73) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL10910387 | 0.76 | RAB9A (0.61) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL5562081 | 0.76 | ALOX15 (0.82) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL4883303 | 0.76 | ALOX15 (0.82) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL30366154 | 0.75 | RAB9A (0.56) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL29286036 | 0.75 | RAB9A (0.56) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL14947177 | 0.75 | RAB9A (0.83) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL1047574 | 0.75 | HSD11B1 (0.52) | ALDH1A1TSHRHSD11B1CYP3A4CYP2D6 | |
| SCHEMBL14585759 | 0.75 | RAB9A (0.83) | RAB9ANPC1KMT2AGAAALDH1A1 | |
| SCHEMBL17122220 | 0.73 | RAB9A (0.80) | RAB9ANPC1KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0825989-A1 | SUBSTITUTED OXAZOLES FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 1998-03-04 | — | — | EP | disclosed |