Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR1 | P21462 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8554553 | 0.83 | PTGS2 (0.66) | FPR1LMNAPTGS2PTGS1GAA | |
| SCHEMBL8554538 | 0.81 | PTGS1 (0.54) | LMNAPTGS2PTGS1ALDH1A1SMN1; SMN2 | |
| SCHEMBL8557299 | 0.80 | PTGS1 (0.53) | FPR1LMNAPTGS2PTGS1GAA | |
| SCHEMBL8556342 | 0.79 | PTGS2 (0.72) | FPR1LMNAPTGS2PTGS1ALDH1A1 | |
| SCHEMBL8552699 | 0.79 | PTGS1 (0.55) | FPR1LMNAPTGS2PTGS1GAA | |
| SCHEMBL8555161 | 0.78 | PTGS2 (0.53) | FPR1LMNAPTGS2PTGS1ALDH1A1 | |
| SCHEMBL8554850 | 0.78 | PTGS2 (0.53) | FPR1LMNAPTGS2PTGS1ALDH1A1 | |
| SCHEMBL8550834 | 0.77 | PTGS2 (0.66) | FPR1LMNAPTGS2PTGS1ALDH1A1 | |
| SCHEMBL8554620 | 0.76 | PTGS1 (0.52) | FPR1LMNAPTGS2PTGS1ALDH1A1 | |
| SCHEMBL8553249 | 0.76 | ADORA3 (0.51) | FPR1LMNAPTGS2PTGS1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |