Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA6 | P23280 | 2/20 | 0.46 |
| ▸ | CA5A | P35218 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8556342 | 0.86 | PTGS2 (0.72) | PTGS1PTGS2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8554553 | 0.84 | PTGS2 (0.66) | PTGS1PTGS2LMNAL3MBTL1 | |
| SCHEMBL8553249 | 0.83 | ADORA3 (0.51) | PTGS1PTGS2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8553129 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8552699 | 0.82 | PTGS1 (0.55) | PTGS1PTGS2ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8552523 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8550834 | 0.82 | PTGS2 (0.66) | PTGS1PTGS2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8551562 | 0.81 | FPR1 (0.52) | PTGS1PTGS2ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21475442 | 0.81 | LMNA (0.53) | ALDH1A1TP53LMNAKMT2AKDM4E | |
| SCHEMBL8554620 | 0.81 | PTGS1 (0.52) | PTGS1PTGS2ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885890-A1 | SULFONYLUREIDOPYRAZOLE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1998-12-23 | — | — | EP | disclosed |