Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.48 |
| ▸ | HTR1F | P30939 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | KIT | P10721 | 1/20 | 0.43 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | FLT1 | P17948 | 1/20 | 0.43 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.43 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL8552469 | 0.87 | TMEM97 (0.42) | TMEM97SIGMAR1MCHR1TRPV1HDAC1 | |
| SCHEMBL8548549 | 0.87 | HTR1F (0.50) | TMEM97SIGMAR1ACKR3HTR1FPDPK1 | |
| SCHEMBL5906460 | 0.83 | HTR1F (0.59) | TMEM97SIGMAR1ACKR3HTR1FHDAC1 | |
| SCHEMBL8551441 | 0.82 | ACKR3 (0.49) | TMEM97SIGMAR1ACKR3HTR1FPDPK1 | |
| SCHEMBL8183280 | 0.82 | HTR1F (0.57) | TMEM97SIGMAR1ACKR3HTR1FPDPK1 | |
| SCHEMBL8552580 | 0.73 | HTR1F (0.65) | HTR1FMCHR1MAPTTP53SMN1; SMN2 | |
| SCHEMBL16548547 | 0.72 | EYA3 (0.53) | — | |
| SCHEMBL8548601 | 0.71 | HTR1F (0.45) | HTR1F | |
| Sulfuric Acid SCHEMBL8551754 | 0.70 | TMEM97 (0.43) | TMEM97SIGMAR1ACKR3MCHR1TRPV1 | |
| SCHEMBL7140234 | 0.70 | HTR1F (0.77) | HTR1FPDPK1CHEK2ABL1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0835869-A2 | New serotonin 5-HT1F agonists | ELI LILLY AND COMPANY (US) | 1998-04-15 | — | — | EP | disclosed |