Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.31 |
| ▸ | VNN1 | O95497 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8356522 | 0.87 | NOTUM (0.38) | ITGB3ITGA2BGFER | |
| SCHEMBL8550693 | 0.83 | HTR2B (0.43) | HRH3ITGB3ITGA2B | |
| SCHEMBL8357011 | 0.77 | ITGB3 (0.46) | HRH3ITGB3ITGA2B | |
| SCHEMBL8553302 | 0.75 | HRH3 (0.41) | HRH3ITGB3ITGA2B | |
| SCHEMBL8589135 | 0.75 | HRH3 (0.44) | HRH3ITGB3ITGA2B | |
| SCHEMBL8593632 | 0.72 | HTR2B (0.45) | HRH3ITGB3ITGA2B | |
| SCHEMBL8552786 | 0.72 | HTR2B (0.45) | HRH3ITGB3ITGA2B | |
| SCHEMBL8356608 | 0.72 | AKR1C3 (0.38) | ITGB3ITGA2B | |
| SCHEMBL8356556 | 0.71 | HRH3 (0.39) | HRH3ITGB3ITGA2B | |
| SCHEMBL7349534 | 0.71 | HRH3 (0.35) | HRH3LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |