Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8553297 | 0.87 | ITGB3 (0.46) | HRH3ITGB3ITGA2BCHRM1LSS | |
| SCHEMBL8644656 | 0.82 | HRH3 (0.39) | HRH3ITGB3ITGA2B | |
| SCHEMBL8356608 | 0.77 | AKR1C3 (0.38) | ITGB3ITGA2BLSS | |
| SCHEMBL9024372 | 0.76 | ITGB3 (0.59) | HRH3ITGB3ITGA2B | |
| SCHEMBL8551745 | 0.75 | HRH3 (0.36) | HRH3ITGB3ITGA2B | |
| SCHEMBL8552905 | 0.74 | SIGMAR1 (0.33) | — | |
| SCHEMBL8592431 | 0.73 | HRH3 (0.45) | HRH3ITGB3ITGA2BLSS | |
| SCHEMBL8595580 | 0.71 | HTR7 (0.34) | HRH3 | |
| SCHEMBL8357011 | 0.71 | ITGB3 (0.46) | HRH3ITGB3ITGA2BCHRM1LSS | |
| SCHEMBL8589135 | 0.70 | HRH3 (0.44) | HRH3ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839147-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1998-05-06 | — | — | EP | disclosed |
| WO-1997003072-A1 | NEW OXAZOLIDINONE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS THAT CONTAIN THESE COMPOUNDS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-01-30 | — | — | WO | disclosed |