Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30306040 | 0.88 | KDM4E (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9107425 | 0.88 | KDM4E (0.50) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9106409 | 0.84 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL510396 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL31238491 | 0.79 | ALDH1A1 (0.66) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL97639 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL888020 | 0.79 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL5050902 | 0.78 | PARP10 (0.65) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL1663469 | 0.78 | PARP10 (0.65) | ALDH1A1MAPTKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9540409 | 0.77 | LMNA (0.43) | ALDH1A1MAPTSMN1; SMN2LMNAF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696585-B1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMA CO LTD (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643931-A | ANTIDIABETIC AGENTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0696585-A1 | NOVEL BISOXADIAZOLIDINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |