Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 4/20 | 0.42 |
| ▸ | F10 | P00742 | 4/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9818059 | 0.84 | TERT (0.46) | KMT2AF2F10PRSS1PRSS2 | |
| SCHEMBL10708134 | 0.84 | L3MBTL1 (0.50) | KMT2AF2F10PRSS1PRSS2 | |
| SCHEMBL11149465 | 0.84 | KDM4E (0.50) | LMNAKMT2AGAAF2F10 | |
| SCHEMBL10988595 | 0.84 | TERT (0.52) | LMNAKMT2AF2F10PRSS1 | |
| SCHEMBL4242644 | 0.82 | LMNA (0.50) | LMNAALDH1A1MAPTHTTMAP4K4 | |
| SCHEMBL11152339 | 0.82 | MAP4K4 (0.49) | LMNAF2F10MAP4K4CYP1A2 | |
| SCHEMBL10989239 | 0.82 | MAP4K4 (0.49) | F2F10ALDH1A1MAPTMAP4K4 | |
| SCHEMBL11383636 | 0.82 | TERT (0.51) | KMT2AF2F10ALDH1A1MAPT | |
| SCHEMBL2521152 | 0.82 | LTA4H (0.58) | KMT2AF2F10PRSS1PRSS2 | |
| SCHEMBL9198034 | 0.81 | F2 (0.42) | KMT2AF2F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4546189-A | Preparation of cyano(6-(substituted phenoxy)-2-pyridinyl)methyl esters of 3-(2,2-dihaloethenyl)-2,2-dimethylcyclopropane carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1985-10-08 | — | — | US | claimed |
| EP-0060838-A4 | CERTAIN 6-CHLORO-2-DI-(SUBSTITUTED PHENOXY) METHYL PYRIDINES. | DOW CHEMICAL CO (US) | 1983-03-23 | — | — | EP | claimed |
| US-4358594-A | Process for preparing certain 6-phenoxy-2-pyridinecarboxaldehydes | THE DOW CHEMICAL CO. (US) | 1982-11-09 | — | — | US | claimed |
| EP-0060838-A1 | CERTAIN 6-CHLORO-2-DI-(SUBSTITUTED PHENOXY) METHYL PYRIDINES | THE DOW CHEMICAL COMPANY (US) | 1982-09-29 | — | — | EP | claimed |
| EP-0058505-A1 | Preparation of esters containing an alpha-cyano group in the alcohol portion of the esters | FMC Corporation (US) | 1982-08-25 | — | — | EP | claimed |
| EP-0050846-A1 | Preparation of cyano (6-(substituted phenoxy)-2-pyridinyl) methyl esters of 3-(2,2-dihaloethenyl)-2,2-dimethyl cyclopropane carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1982-05-05 | — | — | EP | claimed |
| US-4323685-A | Preparation of esters | FMC CORPORATION (US) | 1982-04-06 | — | — | US | claimed |
| WO-1982001003-A1 | CERTAIN 6-CHLORO-2-DI-(SUBSTITUTED PHENOXY)METHYL PYRIDINES | MALHOTRA S | 1982-04-01 | — | — | WO | claimed |
| US-4322535-A | REACTION OF AN ACYL HALIDE, ALDEHYDE, AND CYANIDE SALT USING A CATALYTIC AMPHOTERIC SURFACTANT OF AN AMINO ALKYLSULFONATE | FMC CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| US-4322534-A | Preparation of esters | FMC CORPORATION (US) | 1982-03-30 | — | — | US | claimed |
| US-4281133-A | INSECTICIDES | THE DOW CHEMICAL COMPANY (US) | 1981-07-28 | — | — | US | claimed |
| JP-58018360-A | — | — | None | — | — | JP | disclosed |
| JP-57145860-A | — | — | None | — | — | JP | disclosed |
| JP-59029664-A | — | — | None | — | — | JP | disclosed |
| WO-1993001715-A1 | 1,4-DIARYL-1-CYCLOPROPYL-4-SUBSTITUTED BUTANES AS INSECTICIDES AND ACARICIDES | FMC CORPORATION (US) | 1993-02-04 | — | — | WO | disclosed |
| US-4226872-A | Pyridyl esters of α-substituted amino acids | ZOECON CORPORATION (US) | 1980-10-07 | — | — | US | disclosed |
| US-4224330-A | Esters and thiolesters of benzothienyl acids | ZOECON CORPORATION (US) | 1980-09-23 | — | — | US | disclosed |
| US-4223033-A | Substituted pyridine methyl esters of naphthyl acids | ZOECON CORPORATION (US) | 1980-09-16 | — | — | US | disclosed |
| US-4221799-A | MITICIDES | THE DOW CHEMICAL (US) | 1980-09-09 | — | — | US | disclosed |
| US-4163787-A | Substituted pyridine methyl esters of cyclopropane carboxylic acids and their use as insecticides | THE DOW CHEMICAL COMPANY (US) | 1979-08-07 | — | — | US | disclosed |