Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.42 |
| ▸ | NPY1R | P25929 | 11/20 | 0.37 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8620953 | 0.90 | DGAT2 (0.41) | DGAT2NPY1RPPARGPPARAHRH3 | |
| SCHEMBL8555474 | 0.82 | DGAT2 (0.36) | DGAT2NPY1RPPARGPPARAJAK2 | |
| SCHEMBL8557980 | 0.81 | NPY1R (0.42) | DGAT2NPY1R | |
| SCHEMBL8555848 | 0.80 | DGAT2 (0.39) | DGAT2CHEK2 | |
| SCHEMBL8552592 | 0.80 | GPR119 (0.39) | DGAT2NPY1RCHEK2 | |
| SCHEMBL8552642 | 0.79 | DGAT2 (0.41) | DGAT2PPARGPPARA | |
| SCHEMBL8550720 | 0.78 | NPY1R (0.53) | NPY1R | |
| SCHEMBL8552790 | 0.78 | DGAT2 (0.40) | DGAT2PPARGPPARAJAK2JAK1 | |
| SCHEMBL8555457 | 0.78 | DGAT2 (0.37) | DGAT2CHEK2 | |
| SCHEMBL8552606 | 0.77 | DGAT2 (0.43) | DGAT2NPY1RHRH3CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |