Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT2 | Q96PD7 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 4/20 | 0.34 |
| ▸ | PPARA | Q07869 | 4/20 | 0.34 |
| ▸ | NPY1R | P25929 | 3/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | BCL9 | O00512 | 2/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552790 | 0.87 | DGAT2 (0.40) | DGAT2AKR1C3PPARGPPARAJAK2 | |
| SCHEMBL8620953 | 0.86 | DGAT2 (0.41) | DGAT2PPARGPPARANPY1RJAK2 | |
| SCHEMBL8551796 | 0.82 | DGAT2 (0.42) | DGAT2PPARGPPARANPY1RJAK2 | |
| SCHEMBL8555848 | 0.80 | DGAT2 (0.39) | DGAT2CYP2C9FNTAFNTB | |
| SCHEMBL8552592 | 0.79 | GPR119 (0.39) | DGAT2NPY1RCYP2C9 | |
| SCHEMBL8552979 | 0.79 | NPC1 (0.41) | NPC1PPARGPPARAFAAH | |
| SCHEMBL8552642 | 0.78 | DGAT2 (0.41) | DGAT2PPARGPPARA | |
| SCHEMBL8553272 | 0.77 | MGLL (0.35) | DGAT2 | |
| SCHEMBL8550682 | 0.76 | DGAT2 (0.44) | DGAT2NPY1R | |
| SCHEMBL8555023 | 0.76 | KMT2A (0.35) | NPC1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |