Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 14/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552622 | 0.82 | NPY1R (0.49) | NPY1R | |
| SCHEMBL8551796 | 0.81 | DGAT2 (0.42) | NPY1RDGAT2 | |
| SCHEMBL8554479 | 0.80 | NPY1R (0.45) | NPY1RHRH2HRH1DGAT2FAAH | |
| SCHEMBL8552606 | 0.79 | DGAT2 (0.43) | NPY1RHRH2HRH1ENPP2DGAT2 | |
| SCHEMBL8551336 | 0.77 | GPR119 (0.47) | NPY1RDGAT2FAAH | |
| SCHEMBL8556128 | 0.75 | RAB9A (0.46) | — | |
| SCHEMBL8550720 | 0.75 | NPY1R (0.53) | NPY1R | |
| SCHEMBL8555463 | 0.74 | GPR119 (0.40) | NPY1RDGAT2 | |
| SCHEMBL8550682 | 0.74 | DGAT2 (0.44) | NPY1RHRH2HRH1DGAT2 | |
| SCHEMBL8555784 | 0.73 | RAB9A (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871442-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1997025041-A1 | BENZIMIDZOLYL NEUROPEPTIDE Y RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1997-07-17 | — | — | WO | disclosed |